Fri Aug 15 2025

15 articles - From Friday Aug 08 2025 to Friday Aug 15 2025

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…

Gastroenterology

Canadian Association of Gastroenterology Clinical Practice Guideline for the Endoscopic Management of Nonvariceal Nonpeptic Ulcer Upper Gastrointestinal Bleeding.

For patients with active bleeding from malignant tumors, the panel suggested topical hemostatic agents over conventional endoscopic hemostatic therapy; it also suggested the administration of oncologic therapy after the endoscopic intervention. In patients with active bleeding from MWTs (oozing and spurting), the panel suggested endoscopic band ligation or endoscopic through-the-scope clip over epinephrine injection alone. For nonbleeding MWTs with visible vessels, adherent clots, flat pigmented spots, or clean-based ulcers, the panel suggested against endoscopic hemostatic therapy. For Dieulafoy's lesions, the panel suggested mechanical modalities with endoscopic band ligation or through-the-scope clip, contact thermocoagulation, or injection of sclerosants over epinephrine injection alone. For patients with gastric antral vascular ectasia, the panel suggested endoscopic band ligation over argon plasma coagulation. Guideline endorsement This guideline has been formally endorsed by leading international endoscopy societies the American Society for Gastrointestinal Endoscopy, the European Society of Gastrointestinal Endoscopy, the Sociedad Interamericana de Endoscopía Digestiva, and the World Endoscopy Organization, as well as by the American Gastroenterological Association.

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Meta-analysis

meta-analyses and systematic reviews


Original articles

RCT, clinical trials, retrospective studies, etc…

Aliment Pharmacol Ther

Frequency and Effectiveness of Dose Escalation and De-Escalation of Biologic Therapy in Inflammatory Bowel Disease: The RAINBOW-IBD Study of ENEIDA.

In the long term, some patients with IBD need biologic escalation, which frequently recaptures durable clinical remission. De-escalation is feasible in some patients. Re-escalation is generally effective after relapse.

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Temporal Trends in Medical and Surgical Management of Ulcerative Colitis in England: 2003-2020.

Colectomy in the five years following diagnosis has declined, coinciding with an increased use of advanced therapies. Overall post-operative mortality is low. While the indication for colectomy may influence the risk of adverse outcomes, aggregate data provide a reassuring picture of current practice.

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Clin Gastroenterol Hepatol

Peripancreatic Vascular Involvement and Gastric Varices in Autoimmune Pancreatitis: A Multicenter Retrospective Study.

Peripancreatic vascular involvement represents a common complication of AIP and significantly responds to glucocorticoid therapy, underscoring the importance of careful monitoring to prevent potentially fatal outcomes.

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Risk of Advanced Colorectal Neoplasia at Follow-up Colonoscopy After Synchronous Adenoma and Clinically Significant Serrated Polyp.

Patients with synchronous adenoma and CSSP may have concurrent adenoma-carcinoma and serrated pathways active and are at higher risk of developing advanced neoplasia compared with those with only adenomas. These results may help guide surveillance colonoscopy guidelines specific for those with synchronous adenoma and CSSP.

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J Hepatol

Successful AAV8 gene therapy on hepatic ex situ machine perfusion for mitochondrial neurogastrointestinal encephalomyopathy.

g. gene therapy, in patient's explanted livers.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Aliment Pharmacol Ther

Editorial: Lymphocyte-To-Monocyte Ratio and Recompensation in PBC-A New Piece in an Incomplete Puzzle?

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Clin Gastroenterol Hepatol

Guidance for Timely Referral to Liver Transplantation.

Referral for LT typically begins with primary care providers, gastroenterologists, and oncologists, who can more efficiently deliver their care through understanding of the referral process and LT framework. We aim to provide guidance to adult providers on timely referral to LT, demystify the LT evaluation process and contraindications to LT, and increase partnership between referring providers and transplant center providers caring for patients with advanced chronic liver disease.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Am J Gastroenterol

Correction to: A Stool DNA-Based SDC2 Methylation Test for the Early Detection of Colorectal Cancer in an Asymptomatic, High-Risk Population: A Multicenter Prospective Randomized Trial.

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Gastroenterology

Global Incidence and Prevalence of Inflammatory Bowel Disease Over Time.

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Reveal your sources: Designing training environments to support regulation of learning.

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Hepatology

Letter to the Editor: The CRAPT-M score: Robust enough for clinical practice?

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Letters&Replies

Letters to the editors and authors’ replies

Aliment Pharmacol Ther

Letter on 'Post-TIPS Overt Hepatic Encephalopathy Increases Long-Term but Not Short-Term Mortality in Cirrhotic Patients With Variceal Bleeding: A Large-Scale, Multicentre Real-World'.

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Gastroenterology

Caution Warranted in the Clinical Translation of IgG-Based Elimination Diets for IBS.

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J Hepatol

Not all DOACs are created equal, revisiting the safety of rivaroxaban for the prevention of portal hypertension-related complications.

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